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Transgenic and Knockout Strains of Mice

B&K Universal Ltd hold a library of transgenic/knockout mouse strains which are bred and maintained in isolators to MPF++ status.

We reserve the right to alter the library from time to time to meet current scientific trends and needs.

Mice supplied can be individually identified using microchips, or ear mark/tag. We are also happy to use scientific colleagues’ own microchips. The animals are despatched with a full health status report and background information sheet.

A project licence number may be required at point of order for all transgenic and knockout strains.

Transgenic/knockout and inbred animals often have special husbandry requirements. Before obtaining these animals, advice regarding any special needs should be sought from B&K Universal Ltd.

*We can house transgenic strains and manage a breeding program to meet your specific requirements

Strain, Background* and Reference 
1 IL10T-/- (129Ola x C57Bl6, inbred). Cell 75:263-274. 
2 G129 (IFNg R -/-); (129 SvEv, inbred). Science 259:1742-1745. 
3 A129 (IFNa/b R -/-); (129 SvEv, inbred). Science 264:1918-1921. 
4 AG129 (IFNa/b/g R -/-); (129 SvEv, inbred). J. Virol 69:4792-4796. 
5 Anx-A1-/- (Annexin-A1 null); (Balb/c, inbred). J Physiol Pharmacol 53:541-553. Annexins 1:109-120. 
6 Anx-A1-/- (Annexin-A1 null); (DBA1, inbred). J Physiol Pharmacol 53:541-553. Annexins 1:109-120. 
7 Anx-A1-/- (Annexin-A1 null); (C57Bl/6J, inbred). J Physiol Pharmacol 53:541-553. Annexins 1:109-120. 
8 MtD (Methionine-1 reporter, lines 29 and 34). (Enquire) 
9 SoD2-hCG (hCG reporter, lines 19, 23 and 36). (Enquire) 
10 SoD2-LacZ (LacZ reporter, lines 15 and 18). (Enquire) 
11 Puma (p53 up-regulated modulator of apoptosis). (Enquire) 
*Background (control) strain is denoted in bold text. These are available – see appropriate page in this catalogue.

 

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